TL;DR
Molecular Pharmacology Scientist (Biotech): Supporting flavor ingredient discovery programs, from screening to lead optimization, using in vitro biology assay development. Focus on improving understanding of taste and olfaction and elucidating how receptor-active substances modulate sensory endpoints.
Location: Must be based in Cincinnati, Ohio
Salary: $96,000-$130,000
Company
Givaudan is the global leader in the creation of flavours and fragrances, developing tastes and scents that delight consumers the world over.
What you will do
- Lead in vitro biology assay development to support flavor ingredient discovery programs.
- Guide in vitro biology strategies for exploratory and early-stage discovery efforts.
- Manage experimental design, development, and implementation of cell-based assays for small molecule discovery projects.
- Collaborate with researchers in cheminformatics, chemistry, natural products, and sensory teams.
- Build collaborations with academic partners, CROs, universities, and the broader Givaudan scientific network.
- Present research findings through peer-reviewed publications, scientific meetings, and internal presentations.
Requirements
- PhD in Molecular Pharmacology
- 2–3 years of experience in pharmaceutical or biotechnology industries or 2–3 years of postdoctoral research focused on GPCRs
- In-depth knowledge of receptor pharmacology with practical experience working with GPCRs
- 3+ years of experience with cell-based techniques including Fluorescence Imaging, HTRF, NanoBRET, Tag-Lite, and AlphaScreen
- Expertise in the development of in vitro biological assays supporting small-molecule discovery programs
- Demonstrated scientific rigor in critically reviewing data and independently formulating and testing novel scientific hypotheses
Nice to have
- Experience using AlphaFold and Cryo-EM 3D structural models to interrogate GPCR pharmacology is highly desirable
- Experience managing external studies at CROs or universities
Culture & Benefits
- Contribute to delightful taste and scent experiences that touch people’s lives.
- Work within an inspiring teamwork culture where you can thrive, collaborate, and learn from other talented and passionate people.
- Medical, dental, and vision coverage.
- High-matching 401(k) retirement plan.
